Neurotoxin 101: Understanding the Difference Between Botox, Dysport, Daxxify, Jeuveau, and Letybo

At Coastal Aesthetics, we believe in providing our clients with the knowledge they need to make informed decisions about their treatments. In this guide, we will compare the top neuromodulators to help you understand which one may be best suited for your aesthetic goals.

⸻

How Neuromodulators Work

Neuromodulators are derived from botulinum toxin and function by blocking the nerve signals that cause muscle contractions. By temporarily relaxing targeted facial muscles, they reduce the repetitive movements that lead to dynamic wrinkles, such as forehead lines, frown lines (11s), and crow’s feet.

While all neuromodulators have the same core function, they differ in their formulations, onset times, longevity, and diffusion, which can influence treatment choice.

⸻

Comparing Neuromodulators: Key Differences

Botox® (OnabotulinumtoxinA)

Botox is the original and most widely used neuromodulator, FDA-approved for both medical and cosmetic use. It has a long track record of safety and effectiveness.

    •    Onset: Results typically appear within 3 to 5 days, with full effects in 10 to 14 days

    •    Longevity: Lasts approximately 3 to 4 months

    •    Diffusion: Moderate, allowing for precise placement

    •    Best for: Clients looking for a well-established, consistent option with a strong reputation

⸻

Dysport® (AbobotulinumtoxinA)

Dysport is known for its faster onset and broader diffusion, making it ideal for treating larger areas, such as the forehead.

    •    Onset: Results may appear as early as 24 to 48 hours

    •    Longevity: Typically lasts 3 to 4 months, though some metabolize it slightly faster

    •    Diffusion: Spreads more than Botox, which can be beneficial for softening larger treatment areas

    •    Best for: Clients who want a faster-acting neuromodulator or a softer, more diffused look

⸻

Xeomin® (IncobotulinumtoxinA)

Xeomin is unique in that it does not contain accessory proteins, making it a “naked” neuromodulator. This can be beneficial for individuals who may have developed resistance to Botox or Dysport.

    •    Onset: Similar to Botox, with results appearing in 3 to 5 days

    •    Longevity: Lasts 3 to 4 months

    •    Diffusion: Moderate, like Botox, allowing for targeted precision

    •    Best for: Clients who prefer a purified formulation without additional proteins

⸻

Daxxify® (DaxxibotulinumtoxinA-lanm)

Daxxify is the longest-lasting neuromodulator currently available. It contains a proprietary peptide that helps extend its effects beyond those of other botulinum toxin treatments.

    •    Onset: Results appear within 1 to 2 days, with full effects within a week

    •    Longevity: Can last 6 months or longer, nearly double the duration of other neuromodulators

    •    Diffusion: Similar to Botox, allowing for controlled placement

    •    Best for: Clients seeking longer-lasting results with fewer treatment sessions per year

⸻

Jeuveau® (PrabotulinumtoxinA-xvfs)

Jeuveau, often referred to as “Newtox,” is a newer neuromodulator developed exclusively for aesthetic use.

    •    Onset: Results typically appear within 2 to 4 days

    •    Longevity: Lasts 3 to 4 months

    •    Diffusion: Similar to Botox, making it ideal for precise targeting

    •    Best for: Clients looking for a modern alternative to Botox that is designed specifically for cosmetic applications

⸻

Letybo® (LetibotulinumtoxinA)

Letybo is one of the newest neuromodulators to enter the U.S. market. It is known for its refined formulation and smooth application.

    •    Onset: Results typically appear within 2 to 4 days

    •    Longevity: Lasts about 3 to 4 months

    •    Diffusion: Similar to Botox and Jeuveau, allowing for controlled results

    •    Best for: Clients who want a newer neuromodulator option with precision and smooth effects

⸻

Choosing the Right Neuromodulator for You

While all neuromodulators function in a similar way, the best choice for you depends on several factors, including:

    •    How quickly you want to see results (Dysport and Daxxify work faster than Botox)

    •    How long you want the effects to last (Daxxify offers the longest duration)

    •    The size of the treatment area (Dysport spreads more, while Botox and Xeomin allow for more precise placement)

    •    Whether you prefer a purified formula (Xeomin is free from accessory proteins)

    •    Your budget and treatment goals

At Coastal Aesthetics, we offer a customized approach to neuromodulators, ensuring each client receives a treatment plan tailored to their individual needs. During your consultation, we will assess your skin, discuss your goals, and recommend the best option for you.

⸻

Book Your Neuromodulator Consultation at Coastal Aesthetics

Whether you are new to neuromodulators or looking to explore alternative options, our team is here to guide you. Schedule a consultation today to learn more about how Botox, Dysport, Xeomin, Daxxify, Jeuveau, or Letybo can help you achieve smoother, more youthful-looking skin.